Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase

Many RNA viruses create specialized membranes for genome replication by manipulating host lipid metabolism and trafficking, but in most cases, we do not know the molecular mechanisms responsible or how specific lipids may impact the associated membrane and viral process. For example, hepatitis C vir...

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Detalles Bibliográficos
Autores principales: Tallorin, Lorillee, Villareal, Valerie A., Hsia, Chih-Yun, Rodgers, Mary A., Burri, Dominique J., Pfeil, Marc-Philipp, Llopis, Paula Montero, Lindenbach, Brett D., Yang, Priscilla L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458815/
https://www.ncbi.nlm.nih.gov/pubmed/32641492
http://dx.doi.org/10.1074/jbc.RA120.013455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458815/
https://www.ncbi.nlm.nih.gov/pubmed/32641492
http://dx.doi.org/10.1074/jbc.RA120.013455

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