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A highly efficient non-viral process for programming mesenchymal stem cells for gene directed enzyme prodrug cancer therapy

Mesenchymal stem cells (MSCs) driven gene-directed enzyme prodrug therapy has emerged as a potential strategy for cancer treatment. The tumour-nesting properties of MSCs enable these vehicles to target tumours and metastases with effective therapies. A crucial step in engineering MSCs is the deliver...

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Detalles Bibliográficos
Autores principales: Ho, Yoon Khei, Woo, Jun Yung, Tu, Geraldine Xue En, Deng, Lih-Wen, Too, Heng-Phon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458920/
https://www.ncbi.nlm.nih.gov/pubmed/32868813
http://dx.doi.org/10.1038/s41598-020-71224-2