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A highly efficient non-viral process for programming mesenchymal stem cells for gene directed enzyme prodrug cancer therapy
Mesenchymal stem cells (MSCs) driven gene-directed enzyme prodrug therapy has emerged as a potential strategy for cancer treatment. The tumour-nesting properties of MSCs enable these vehicles to target tumours and metastases with effective therapies. A crucial step in engineering MSCs is the deliver...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458920/ https://www.ncbi.nlm.nih.gov/pubmed/32868813 http://dx.doi.org/10.1038/s41598-020-71224-2 |