Cargando…
A highly efficient non-viral process for programming mesenchymal stem cells for gene directed enzyme prodrug cancer therapy
Mesenchymal stem cells (MSCs) driven gene-directed enzyme prodrug therapy has emerged as a potential strategy for cancer treatment. The tumour-nesting properties of MSCs enable these vehicles to target tumours and metastases with effective therapies. A crucial step in engineering MSCs is the deliver...
Autores principales: | Ho, Yoon Khei, Woo, Jun Yung, Tu, Geraldine Xue En, Deng, Lih-Wen, Too, Heng-Phon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458920/ https://www.ncbi.nlm.nih.gov/pubmed/32868813 http://dx.doi.org/10.1038/s41598-020-71224-2 |
Ejemplares similares
-
A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
por: Tu, Geraldine Xue En, et al.
Publicado: (2020) -
Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment
por: Ho, Yoon Khei, et al.
Publicado: (2022) -
Direct Quantification of mRNA and miRNA from Cell Lysates Using Reverse Transcription Real Time PCR: A Multidimensional Analysis of the Performance of Reagents and Workflows
por: Ho, Yoon Khei, et al.
Publicado: (2013) -
Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of β-tubulin deactylase
por: Ho, Yoon Khei, et al.
Publicado: (2017) -
Enhanced transfection of a macromolecular lignin-based DNA complex with low cellular toxicity
por: Ho, Yoon Khei, et al.
Publicado: (2018)