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Intestinal epithelial plasticity and regeneration via cell dedifferentiation
The intestinal epithelium possesses a great capacity of self-renewal under normal homeostatic conditions and of regeneration upon damages. The renewal and regenerative processes are driven by intestinal stem cells (ISCs), which reside at the base of crypts and are marked by Lgr5. As Lgr5(+) ISCs und...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459029/ https://www.ncbi.nlm.nih.gov/pubmed/32869114 http://dx.doi.org/10.1186/s13619-020-00053-5 |