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Intestinal epithelial plasticity and regeneration via cell dedifferentiation

The intestinal epithelium possesses a great capacity of self-renewal under normal homeostatic conditions and of regeneration upon damages. The renewal and regenerative processes are driven by intestinal stem cells (ISCs), which reside at the base of crypts and are marked by Lgr5. As Lgr5(+) ISCs und...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Chen, Ye-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459029/
https://www.ncbi.nlm.nih.gov/pubmed/32869114
http://dx.doi.org/10.1186/s13619-020-00053-5