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Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis
Osteoarthritis (OA) is a condition associated with severe inflammation, cartilage destruction and degeneration of joints. Rhein (Rh) is an effective anti-inflammatory drug with proven efficacy in in-vitro and in-vivo models. pH sensitive Rh and NH(4)HCO(3) laden poly (lactic-co-glycolic acid (PLGA)...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459081/ https://www.ncbi.nlm.nih.gov/pubmed/32865763 http://dx.doi.org/10.1186/s13568-020-01095-3 |