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Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis

Osteoarthritis (OA) is a condition associated with severe inflammation, cartilage destruction and degeneration of joints. Rhein (Rh) is an effective anti-inflammatory drug with proven efficacy in in-vitro and in-vivo models. pH sensitive Rh and NH(4)HCO(3) laden poly (lactic-co-glycolic acid (PLGA)...

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Detalles Bibliográficos
Autores principales:	Hu, Bo, Gao, Feng, Li, Chunbao, Zhang, Boqing, An, Mingyang, Lu, Ming, Liu, Yufeng, Liu, Yujie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459081/ https://www.ncbi.nlm.nih.gov/pubmed/32865763 http://dx.doi.org/10.1186/s13568-020-01095-3

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