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Prevalence and clinical implications of germline predisposition gene mutations in patients with acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most common types of leukemia. With the recent advances in sequencing technology and the growing body of knowledge on the genetics of AML, there is increasing concern about cancer predisposing germline mutations as well as somatic mutations. As familial cas...

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Detalles Bibliográficos
Autores principales: Kim, Borahm, Yun, Woobin, Lee, Seung-Tae, Choi, Jong Rok, Yoo, Keon Hee, Koo, Hong Hoe, Jung, Chul Won, Kim, Sun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459095/
https://www.ncbi.nlm.nih.gov/pubmed/32868804
http://dx.doi.org/10.1038/s41598-020-71386-z