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Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients

This study compared the tumor immune microenvironments (TIMEs) of primary gastric cancer (PGC) and paired metastatic gastric cancer (MGC). CD4(+) and CD8(+) T-cell density and PD-L1 expression were evaluated by multiplex immunohistochemistry, DNA mismatch repair (MMR) by immunohistochemistry, and im...

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Detalles Bibliográficos
Autores principales: Son, Seung-Myoung, Woo, Chang Gok, Kim, Dae Hoon, Yun, Hyo Yung, Kim, Hongsik, Kim, Hee Kyung, Yang, Yaewon, Kwon, Jihyun, Kwon, Minsuk, Kim, Tae-Yong, Kim, Hyung-Don, Koh, June-Young, Park, Su-Hyung, Shin, Eui-Cheol, Han, Hye Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459099/
https://www.ncbi.nlm.nih.gov/pubmed/32868848
http://dx.doi.org/10.1038/s41598-020-71340-z