Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses

Increased extracellular sodium activates Th17 cells, which provide protection from bacterial and fungal infections. Whilst high salt diets have been shown to worsen autoimmune disease, the immunological consequences of clinical salt depletion are unknown. Here, we investigate immunity in patients wi...

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Detalles Bibliográficos
Autores principales: Evans, Rhys D. R., Antonelou, Marilina, Sathiananthamoorthy, Sanchutha, Rega, Marilena, Henderson, Scott, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Müller, Christoph A., Doffinger, Rainer, Walsh, Stephen B., Salama, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459119/
https://www.ncbi.nlm.nih.gov/pubmed/32868758
http://dx.doi.org/10.1038/s41467-020-18184-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459119/
https://www.ncbi.nlm.nih.gov/pubmed/32868758
http://dx.doi.org/10.1038/s41467-020-18184-3

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