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Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses
Increased extracellular sodium activates Th17 cells, which provide protection from bacterial and fungal infections. Whilst high salt diets have been shown to worsen autoimmune disease, the immunological consequences of clinical salt depletion are unknown. Here, we investigate immunity in patients wi...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459119/ https://www.ncbi.nlm.nih.gov/pubmed/32868758 http://dx.doi.org/10.1038/s41467-020-18184-3 |