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Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19

Thrombin is a trypsin-like serine protease with multiple physiological functions. Its role in coagulation and thrombosis is well-established. Nevertheless, thrombin also plays a major role in inflammation by activating protease-activated receptors. In addition, thrombin is also involved in angiogene...

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Detalles Bibliográficos
Autores principales: Aliter, Kholoud F., Al-Horani, Rami A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459262/
https://www.ncbi.nlm.nih.gov/pubmed/32870433
http://dx.doi.org/10.1007/s10557-020-07066-x