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Cerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors

Serum and cerebrospinal fluid (CSF) levels of α-fetoprotein and β-subunit of human chorionic gonadotropin are used as biomarkers for the management of central nervous system (CNS) germ cell tumors (GCTs). However, additional discriminating biomarkers are required. Especially, biomarkers to different...

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Detalles Bibliográficos
Autores principales: Takayasu, Takeshi, Shah, Mauli, Dono, Antonio, Yan, Yuanqing, Borkar, Roshan, Putluri, Nagireddy, Zhu, Jay-Jiguang, Hama, Seiji, Yamasaki, Fumiyuki, Tahara, Hidetoshi, Sugiyama, Kazuhiko, Kurisu, Kaoru, Esquenazi, Yoshua, Ballester, Leomar Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459305/
https://www.ncbi.nlm.nih.gov/pubmed/32868820
http://dx.doi.org/10.1038/s41598-020-71161-0