CXCR4(hi) effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4(hi) neutrophil polarization

Leukocyte recruitment and heterocellular aggregate formation drive the inflammatory vaso-occlusive processes associated with sickle cell anemia (SCA). We characterized neutrophils in a population of patients with SCA and investigated whether platelet-derived molecules can induce phenotypic alteratio...

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Detalles Bibliográficos
Autores principales: Garcia, Flavia, Mendonça, Rafaela, Miguel, Lediana I., Dominical, Venina M., Saad, Sara T. O., Costa, Fernando F., Conran, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459317/
https://www.ncbi.nlm.nih.gov/pubmed/32868775
http://dx.doi.org/10.1038/s41598-020-71078-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459317/
https://www.ncbi.nlm.nih.gov/pubmed/32868775
http://dx.doi.org/10.1038/s41598-020-71078-8

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