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CXCR4(hi) effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4(hi) neutrophil polarization

Leukocyte recruitment and heterocellular aggregate formation drive the inflammatory vaso-occlusive processes associated with sickle cell anemia (SCA). We characterized neutrophils in a population of patients with SCA and investigated whether platelet-derived molecules can induce phenotypic alteratio...

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Detalles Bibliográficos
Autores principales:	Garcia, Flavia, Mendonça, Rafaela, Miguel, Lediana I., Dominical, Venina M., Saad, Sara T. O., Costa, Fernando F., Conran, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459317/ https://www.ncbi.nlm.nih.gov/pubmed/32868775 http://dx.doi.org/10.1038/s41598-020-71078-8

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