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Down‐regulation of PDGFRβ suppresses invasion and migration in osteosarcoma cells by influencing epithelial–mesenchymal transition

Osteosarcoma (OS) is the most common malignant bone tumor primarily influencing children and adults. Approximately one‐fifth of patients have micrometastasis in the lungs when OS is diagnosed. Platelet‐derived growth factor receptor (PDGFR) beta (PDGFRβ) is a subtype of PDGFR. PDGFRβ has been noted...

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Detalles Bibliográficos
Autores principales: Xing, Sining, Wang, Changdong, Tang, Huying, Guo, Jiaqi, Liu, Xing, Yi, Faping, Liu, Geli, Wu, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459394/
https://www.ncbi.nlm.nih.gov/pubmed/32580247
http://dx.doi.org/10.1002/2211-5463.12915