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ADAMTS7 degrades Comp to fuel BMP2‐dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents, with a high metastatic potential. Despite dramatic changes in OS treatments over the past decades, their efficiency still remains limited, with severe complications and adverse side effects. Key mechanisms...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Chen, Yunqing, Xiang, Hongfei, Wu, Xiaolin, Tang, Qian, Ma, Xuexiao, Zhang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459396/
https://www.ncbi.nlm.nih.gov/pubmed/32692461
http://dx.doi.org/10.1002/2211-5463.12939