Optimized high‐fidelity 3DPCR to assess potential mitochondrial targeting by activation‐induced cytidine deaminase

Activation‐induced cytidine deaminase (AID) initiates somatic hypermutation and class switch recombination of immunoglobulin genes in B cells, whereas off‐targeted AID activity contributes to oncogenic mutations and chromosomal translocations associated with B cell malignancies. Paradoxically, only...

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Detalles Bibliográficos
Autores principales: Wu, Haiyan, Zhang, Kaili, Chen, Yue, Li, Jinfeng, Strout, Matthew P., Gu, Xiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459399/
https://www.ncbi.nlm.nih.gov/pubmed/32633086
http://dx.doi.org/10.1002/2211-5463.12927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459399/
https://www.ncbi.nlm.nih.gov/pubmed/32633086
http://dx.doi.org/10.1002/2211-5463.12927

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