Structural insights into the enhanced carbapenemase efficiency of OXA‐655 compared to OXA‐10

Carbapenemases are the main cause of carbapenem resistance in Gram‐negative bacteria. How β‐lactamases with weak carbapenemase activity, such as the OXA‐10‐type class D β‐lactamases, contribute to anti‐bacterial drug resistance is unclear. OXA‐655 is a T26M and V117L OXA‐10 variant, recently identif...

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Detalles Bibliográficos
Autores principales: Leiros, Hanna‐Kirsti S., Thomassen, Ane Molden, Samuelsen, Ørjan, Flach, Carl‐Fredrik, Kotsakis, Stathis D., Larsson, D.G. Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459404/
https://www.ncbi.nlm.nih.gov/pubmed/32683794
http://dx.doi.org/10.1002/2211-5463.12935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459404/
https://www.ncbi.nlm.nih.gov/pubmed/32683794
http://dx.doi.org/10.1002/2211-5463.12935

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