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S‐allyl‐L‐cysteine protects hepatocytes from indomethacin‐induced apoptosis by attenuating endoplasmic reticulum stress

Drug‐induced liver injury (DILI) can lead to acute liver failure, a lethal condition which may require liver transplantation. Hepatotoxicity associated with nonsteroidal anti‐inflammatory drugs (NSAIDs) accounts for ~ 10% of all DILI. In the current study, we determined whether indomethacin, one of...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Chen, Chen, Hu, Mingdao, Cui, Rui, Liu, Feng, Yu, Henghai, Ren, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459406/
https://www.ncbi.nlm.nih.gov/pubmed/32790969
http://dx.doi.org/10.1002/2211-5463.12945