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Alzheimer's disease risk modifier genes do not affect tau aggregate uptake, seeding or maintenance in cell models

Alzheimer's disease (AD) afflicts millions of people worldwide and is caused by accumulated amyloid beta and tau pathology. Progression of tau pathology in AD may utilize prion mechanisms of propagation in which pathological tau aggregates released from one cell are taken up by neighboring or c...

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Detalles Bibliográficos
Autores principales: Kolay, Sourav, Diamond, Marc I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459407/
https://www.ncbi.nlm.nih.gov/pubmed/32649026
http://dx.doi.org/10.1002/2211-5463.12928