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Translation of small downstream ORFs enhances translation of canonical main open reading frames
In addition to canonical open reading frames (ORFs), thousands of translated small ORFs (containing less than 100 codons) have been identified in untranslated mRNA regions (UTRs) across eukaryotes. Small ORFs in 5′ UTRs (upstream (u)ORFs) often repress translation of the canonical ORF within the sam...
Autores principales: | Wu, Qiushuang, Wright, Matthew, Gogol, Madelaine M, Bradford, William D, Zhang, Ning, Bazzini, Ariel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459409/ https://www.ncbi.nlm.nih.gov/pubmed/32744758 http://dx.doi.org/10.15252/embj.2020104763 |
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