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Tracking leukemic T‐cell transcriptional dynamics in vivo with a blood‐based reporter assay
Transcriptional dynamics of cancer cells govern cell fate decisions and are therapeutically actionable drug targets. In this study, we engineered a circulating cancer cell line that secretes a luciferase reporter to capture constitutive and circadian clock‐driven transcription dynamics over the cour...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459418/ https://www.ncbi.nlm.nih.gov/pubmed/32710494 http://dx.doi.org/10.1002/2211-5463.12940 |