A small targeting domain in Ty1 integrase is sufficient to direct retrotransposon integration upstream of tRNA genes

Integration of transposable elements into the genome is mutagenic. Mechanisms targeting integrations into relatively safe locations, hence minimizing deleterious consequences for cell fitness, have emerged during evolution. In budding yeast, integration of the Ty1 LTR retrotransposon upstream of RNA...

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Detalles Bibliográficos
Autores principales: Asif‐Laidin, Amna, Conesa, Christine, Bonnet, Amandine, Grison, Camille, Adhya, Indranil, Menouni, Rachid, Fayol, Hélène, Palmic, Noé, Acker, Joël, Lesage, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459421/
https://www.ncbi.nlm.nih.gov/pubmed/32677087
http://dx.doi.org/10.15252/embj.2019104337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459421/
https://www.ncbi.nlm.nih.gov/pubmed/32677087
http://dx.doi.org/10.15252/embj.2019104337

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