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A small targeting domain in Ty1 integrase is sufficient to direct retrotransposon integration upstream of tRNA genes
Integration of transposable elements into the genome is mutagenic. Mechanisms targeting integrations into relatively safe locations, hence minimizing deleterious consequences for cell fitness, have emerged during evolution. In budding yeast, integration of the Ty1 LTR retrotransposon upstream of RNA...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459421/ https://www.ncbi.nlm.nih.gov/pubmed/32677087 http://dx.doi.org/10.15252/embj.2019104337 |