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Systematic analysis of the IL‐17 receptor signalosome reveals a robust regulatory feedback loop

IL‐17 mediates immune protection from fungi and bacteria, as well as it promotes autoimmune pathologies. However, the regulation of the signal transduction from the IL‐17 receptor (IL‐17R) remained elusive. We developed a novel mass spectrometry‐based approach to identify components of the IL‐17R co...

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Detalles Bibliográficos
Autores principales: Draberova, Helena, Janusova, Sarka, Knizkova, Daniela, Semberova, Tereza, Pribikova, Michaela, Ujevic, Andrea, Harant, Karel, Knapkova, Sofija, Hrdinka, Matous, Fanfani, Viola, Stracquadanio, Giovanni, Drobek, Ales, Ruppova, Klara, Stepanek, Ondrej, Draber, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459424/
https://www.ncbi.nlm.nih.gov/pubmed/32696476
http://dx.doi.org/10.15252/embj.2019104202