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Control of Persistent Salmonella Infection Relies on Constant Thymic Output Despite Increased Peripheral Antigen-Specific T Cell Immunity

Recent thymic emigrants are the youngest subset of peripheral T cells and their involvement in combating persistent bacterial infections has not been explored. Here, we hypothesized that CD4(+) recent thymic emigrants are essential immune mediators during persistent Salmonella infection. To test thi...

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Detalles Bibliográficos
Autores principales: Goggins, J. Alan, Kurtz, Jonathan R, McLachlan, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459538/
https://www.ncbi.nlm.nih.gov/pubmed/32722409
http://dx.doi.org/10.3390/pathogens9080605