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H9N2 Influenza Virus Infections in Human Cells Require a Balance between Neuraminidase Sialidase Activity and Hemagglutinin Receptor Affinity

Some avian influenza (AI) viruses have a deletion of up to 20 to 30 amino acids in their neuraminidase (NA) stalk. This has been associated with changes in virus replication and host range. Currently prevalent H9N2 AI viruses have only a 2- or 3-amino-acid deletion, and such deletions were detected...

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Detalles Bibliográficos
Autores principales: Arai, Yasuha, Elgendy, Emad Mohamed, Daidoji, Tomo, Ibrahim, Madiha Salah, Ono, Takao, Sriwilaijaroen, Nongluk, Suzuki, Yasuo, Nakaya, Takaaki, Matsumoto, Kazuhiko, Watanabe, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459563/
https://www.ncbi.nlm.nih.gov/pubmed/32641475
http://dx.doi.org/10.1128/JVI.01210-20