Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer’s Disease in the AIBL Study of Ageing

In response to double-stranded breaks (DSBs) in chromosomal DNA, H2AX (a member of histone H2A family) becomes phosphorylated to form γH2AX. Although increased levels of γH2AX have been reported in the neuronal nuclei of Alzheimer’s disease (AD) patients, the understanding of γH2AX responses in bucc...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mohammad Sabbir, Francois, Maxime, Rainey-Smith, Stephanie, Martins, Ralph, Masters, Colin L., Ames, David, Rowe, Christopher C., Macaulay, Lance S., Fenech, Michael F., Leifert, Wayne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459751/
https://www.ncbi.nlm.nih.gov/pubmed/32781776
http://dx.doi.org/10.3390/life10080141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459751/
https://www.ncbi.nlm.nih.gov/pubmed/32781776
http://dx.doi.org/10.3390/life10080141

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