Transmissible Endosomal Intoxication: A Balance between Exosomes and Lysosomes at the Basis of Intercellular Amyloid Propagation

In Alzheimer′s disease (AD), endolysosomal dysfunctions are amongst the earliest cellular features to appear. Each organelle of the endolysosomal system, from the multivesicular body (MVB) to the lysosome, contributes to the homeostasis of amyloid precursor protein (APP) cleavage products including...

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Detalles Bibliográficos
Autores principales: Bécot, Anaïs, Volgers, Charlotte, van Niel, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459801/
https://www.ncbi.nlm.nih.gov/pubmed/32759666
http://dx.doi.org/10.3390/biomedicines8080272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459801/
https://www.ncbi.nlm.nih.gov/pubmed/32759666
http://dx.doi.org/10.3390/biomedicines8080272

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