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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities

Background: Schistosomiasis, caused by infection with blood fluke schistosomes, is a neglected tropical disease of considerable importance in resource-poor communities throughout the developing world. In the absence of an immunoprophylactic vaccine and due to over-reliance on a single chemotherapy (...

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Detalles Bibliográficos
Autores principales: Padalino, Gilda, Chalmers, Iain W., Brancale, Andrea, Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459852/
https://www.ncbi.nlm.nih.gov/pubmed/32904763
http://dx.doi.org/10.12688/wellcomeopenres.16069.2