Oral Ingestion of Synthetically Generated Recombinant Prion Is Sufficient to Cause Prion Disease in Wild-Type Mice

Prion disease is a group of transmissible neurodegenerative disorders affecting humans and animals. The prion hypothesis postulates that PrP(Sc), the pathogenic conformer of host-encoded prion protein (PrP), is the unconventional proteinaceous infectious agent called prion. Supporting this hypothesi...

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Detalles Bibliográficos
Autores principales: Pan, Chenhua, Yang, Junwei, Zhang, Xiangyi, Chen, Ying, Wei, Shunxiong, Yu, Guohua, Pan, Yi-Hsuan, Ma, Jiyan, Yuan, Chonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459977/
https://www.ncbi.nlm.nih.gov/pubmed/32823763
http://dx.doi.org/10.3390/pathogens9080653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459977/
https://www.ncbi.nlm.nih.gov/pubmed/32823763
http://dx.doi.org/10.3390/pathogens9080653

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