N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity

Oligodendrocytic injury by oxidative stress can lead to demyelination, contributing to neurodegeneration. We investigated the mechanisms by which an antioxidant, N-acetylcysteine (NAC), reduces oxidative stress in murine oligodendrocytes. We used normal 158N and mutant 158JP cells with endogenously...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Terluk, Marcia R., Basso, Lisa, Mishra, Usha R., Orchard, Paul J., Cloyd, James C., Schröder, Henning, Kartha, Reena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460204/
https://www.ncbi.nlm.nih.gov/pubmed/32717964
http://dx.doi.org/10.3390/biomedicines8080240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460204/
https://www.ncbi.nlm.nih.gov/pubmed/32717964
http://dx.doi.org/10.3390/biomedicines8080240

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