New Cytotoxic Cerebrosides from the Red Sea Cucumber Holothuria spinifera Supported by In-Silico Studies

Bioactivity-guided fractionation of a methanolic extract of the Red Sea cucumber Holothuria spinifera and LC-HRESIMS-assisted dereplication resulted in the isolation of four compounds, three new cerebrosides, spiniferosides A (1), B (2), and C (3), and cholesterol sulfate (4). The chemical structure...

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Detalles Bibliográficos
Autores principales: Abdelhameed, Reda F. A., Eltamany, Enas E., Hal, Dina M., Ibrahim, Amany K., AboulMagd, Asmaa M., Al-Warhi, Tarfah, Youssif, Khayrya A., Abd El-kader, Adel M., Hassanean, Hashim A., Fayez, Shaimaa, Bringmann, Gerhard, Ahmed, Safwat A., Abdelmohsen, Usama Ramadan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460232/
https://www.ncbi.nlm.nih.gov/pubmed/32752177
http://dx.doi.org/10.3390/md18080405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460232/
https://www.ncbi.nlm.nih.gov/pubmed/32752177
http://dx.doi.org/10.3390/md18080405

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