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Omega-3 Fatty Acid-Enriched Fish Oil and Selenium Combination Modulates Endoplasmic Reticulum Stress Response Elements and Reverses Acquired Gefitinib Resistance in HCC827 Lung Adenocarcinoma Cells

Non-small cell lung cancer (NSCLC)-carrying specific epidermal growth factor receptor (EGFR) mutations can be effectively treated by a tyrosine kinase inhibitor such as gefitinib. However, the inevitable development of acquired resistance leads to the eventual failure of therapy. In this study, we s...

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Detalles Bibliográficos
Autores principales: Liao, Chien-Huang, Tzeng, Yu-Tien, Lai, Gi-Ming, Chang, Chia-Lun, Hu, Ming-Hung, Tsai, Wei-Lun, Liu, Yun-Ru, Hsia, Simon, Chuang, Shuang-En, Chiou, Tzeon-Jye, Wang, Le-Ming, Whang-Peng, Jacqueline, Yao, Chih-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460277/
https://www.ncbi.nlm.nih.gov/pubmed/32751169
http://dx.doi.org/10.3390/md18080399