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2,4-Diamino-Quinazoline, a Wnt Signaling Inhibitor, Suppresses Gastric Cancer Progression and Metastasis

Gastric cancer (GC) is among the most treatment-refractory epithelial malignancies. Aberrant activation of Wnt/β-catenin-signaling has been implicated in a variety of human cancers, including gastric cancer. Here we report that the elevated expression of lymphoid enhancer binding factor 1 (Lef1) is...

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Detalles Bibliográficos
Autores principales: Chang, Te-Sheng, Lu, Chung-Kuang, Hsieh, Yung-Yu, Wei, Kuo-Liang, Chen, Wei-Ming, Tung, Sui-Yi, Wu, Cheng-Shyong, Chan, Michael W. Y., Chiang, Ming-Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460562/
https://www.ncbi.nlm.nih.gov/pubmed/32824603
http://dx.doi.org/10.3390/ijms21165901