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P38 Regulates Kainic Acid-Induced Seizure and Neuronal Firing via Kv4.2 Phosphorylation
The subthreshold, transient A-type K(+) current is a vital regulator of the excitability of neurons throughout the brain. In mammalian hippocampal pyramidal neurons, this current is carried primarily by ion channels comprising Kv4.2 α-subunits. These channels occupy the somatodendritic domains of th...
Autores principales: | Hu, Jia-hua, Malloy, Cole, Hoffman, Dax A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460594/ https://www.ncbi.nlm.nih.gov/pubmed/32824677 http://dx.doi.org/10.3390/ijms21165921 |
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