How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs

G protein-coupled receptors (GPCRs) are implicated in nearly every physiological process in the human body and therefore represent an important drug targeting class. Advances in X-ray crystallography and cryo-electron microscopy (cryo-EM) have provided multiple static structures of GPCRs in complex...

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Detalles Bibliográficos
Autores principales: Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Aranda-García, David, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460635/
https://www.ncbi.nlm.nih.gov/pubmed/32824756
http://dx.doi.org/10.3390/ijms21165933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460635/
https://www.ncbi.nlm.nih.gov/pubmed/32824756
http://dx.doi.org/10.3390/ijms21165933

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