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How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs
G protein-coupled receptors (GPCRs) are implicated in nearly every physiological process in the human body and therefore represent an important drug targeting class. Advances in X-ray crystallography and cryo-electron microscopy (cryo-EM) have provided multiple static structures of GPCRs in complex...
Autores principales: | Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Aranda-García, David, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Selent, Jana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460635/ https://www.ncbi.nlm.nih.gov/pubmed/32824756 http://dx.doi.org/10.3390/ijms21165933 |
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