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Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells

Calcium ions regulate a wide array of physiological functions including cell differentiation, proliferation, muscle contraction, neurotransmission, and fertilization. The endoplasmic reticulum (ER) is the major intracellular Ca(2+) store and cellular events that induce ER store depletion (e.g., acti...

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Detalles Bibliográficos
Autores principales: Schild, Achille, Bhardwaj, Rajesh, Wenger, Nicolas, Tscherrig, Dominic, Kandasamy, Palanivel, Dernič, Jan, Baur, Roland, Peinelt, Christine, Hediger, Matthias A., Lochner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460636/
https://www.ncbi.nlm.nih.gov/pubmed/32764353
http://dx.doi.org/10.3390/ijms21165604