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Interactions between the Intrinsically Disordered Regions of hnRNP-A2 and TDP-43 Accelerate TDP-43′s Conformational Transition

Most biological functions involve protein–protein interactions. Our understanding of these interactions is based mainly on those of structured proteins, because encounters between intrinsically disordered proteins (IDPs) or proteins with intrinsically disordered regions (IDRs) are much less studied,...

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Detalles Bibliográficos
Autores principales: Chiang, Wan-Chin, Lee, Ming-Hsuan, Chen, Tsai-Chen, Huang, Jie-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460674/
https://www.ncbi.nlm.nih.gov/pubmed/32824743
http://dx.doi.org/10.3390/ijms21165930