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The Essential Role of Peptidylarginine Deiminases 2 for Cytokines Secretion, Apoptosis, and Cell Adhesion in Macrophage

Objective: The study aims to investigate the functional roles of peptidylarginine deiminase 2 (PADI2) in macrophages. Methods: The clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein-9 nuclease (Cas9) system was used to knockout PADI2 in U937 cells. U937 cell...

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Detalles Bibliográficos
Autores principales: Yu, Hui-Chun, Tung, Chien-Hsueh, Huang, Kuang-Yung, Huang, Hsien-Bin, Lu, Ming-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460808/
https://www.ncbi.nlm.nih.gov/pubmed/32785008
http://dx.doi.org/10.3390/ijms21165720