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Focal Adhesion Kinase (FAK) Over-Expression and Prognostic Implication in Pediatric Hepatocellular Carcinoma

Focal adhesion kinase (FAK) is over-expressed and is correlated with aggressiveness in adult hepatocellular carcinoma (HCC). Inhibition of FAK decreases HCC invasiveness by down-regulating Enhancer of Zeste homolog 2 (EZH2), an epigenetic controller, that acts in transcriptional repression of a larg...

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Detalles Bibliográficos
Autores principales: Francalanci, Paola, Giovannoni, Isabella, De Stefanis, Cristiano, Romito, Ilaria, Grimaldi, Chiara, Castellano, Aurora, D’Oria, Valentina, Alaggio, Rita, Alisi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460809/
https://www.ncbi.nlm.nih.gov/pubmed/32806748
http://dx.doi.org/10.3390/ijms21165795