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Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

Background: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain peripheral tolerance through presentation of peripheral tissue antigens (PTAs)....

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Detalles Bibliográficos
Autores principales: Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke A., Semmelink, Johanna F., Remmerswaal, Ester B. M., Safy, Mary, van Lienden, Krijn P., Maas, Mario, Gerlag, Danielle M., Tak, Paul P., Mebius, Reina E., Wähämaa, Heidi, Catrina, Anca I., G. M. van Baarsen, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460812/
https://www.ncbi.nlm.nih.gov/pubmed/32784936
http://dx.doi.org/10.3390/ijms21165713