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Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis
Background: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain peripheral tolerance through presentation of peripheral tissue antigens (PTAs)....
Autores principales: | Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke A., Semmelink, Johanna F., Remmerswaal, Ester B. M., Safy, Mary, van Lienden, Krijn P., Maas, Mario, Gerlag, Danielle M., Tak, Paul P., Mebius, Reina E., Wähämaa, Heidi, Catrina, Anca I., G. M. van Baarsen, Lisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460812/ https://www.ncbi.nlm.nih.gov/pubmed/32784936 http://dx.doi.org/10.3390/ijms21165713 |
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