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Thymus Inception: Molecular Network in the Early Stages of Thymus Organogenesis

The thymus generates central immune tolerance by producing self-restricted and self-tolerant T-cells as a result of interactions between the developing thymocytes and the stromal microenvironment, mainly formed by the thymic epithelial cells. The thymic epithelium derives from the endoderm of the ph...

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Detalles Bibliográficos
Autores principales: Figueiredo, Marta, Zilhão, Rita, Neves, Hélia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460828/
https://www.ncbi.nlm.nih.gov/pubmed/32796710
http://dx.doi.org/10.3390/ijms21165765