CA9 Silencing Promotes Mitochondrial Biogenesis, Increases Putrescine Toxicity and Decreases Cell Motility to Suppress ccRCC Progression

Carbonic anhydrase IX (CA9), a pH-regulating transmembrane protein, is highly expressed in solid tumors, and particularly in clear cell renal cell carcinoma (ccRCC). The catalytic mechanisms of CA9 are well defined, but its roles in mediating cell migration/invasion and survival in ccRCC remain to b...

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Detalles Bibliográficos
Autores principales: Xu, Jiatong, Zhu, Songbiao, Xu, Lina, Liu, Xiaohui, Ding, Wenxi, Wang, Qingtao, Chen, Yuling, Deng, Haiteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460829/
https://www.ncbi.nlm.nih.gov/pubmed/32824856
http://dx.doi.org/10.3390/ijms21165939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460829/
https://www.ncbi.nlm.nih.gov/pubmed/32824856
http://dx.doi.org/10.3390/ijms21165939

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