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PTEN Is Required for The Anti-Epileptic Effects of AMPA Receptor Antagonists in Chronic Epileptic Rats

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is one of the ligand-gated ion channels for glutamate, which is an important player in the generation and spread of seizures. The efficacy of AMPAR functionality is regulated by the trafficking, synaptic targeting, and phosphoryla...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Park, Hana, Lee, Ji-Eun, Kim, Tae-Hyun, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460838/
https://www.ncbi.nlm.nih.gov/pubmed/32781725
http://dx.doi.org/10.3390/ijms21165643