Plasticity of the 340-Loop in Influenza Neuraminidase Offers New Insight for Antiviral Drug Development

The recently discovered 340-cavity in influenza neuraminidase (NA) N6 and N7 subtypes has introduced new possibilities for rational structure-based drug design. However, the plasticity of the 340-loop (residues 342–347) and the role of the 340-loop in NA activity and substrate binding have not been...

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Detalles Bibliográficos
Autores principales: Han, Nanyu, Ng, Justin Tze Yang, Li, Yanpeng, Mu, Yuguang, Huang, Zunxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460844/
https://www.ncbi.nlm.nih.gov/pubmed/32781779
http://dx.doi.org/10.3390/ijms21165655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460844/
https://www.ncbi.nlm.nih.gov/pubmed/32781779
http://dx.doi.org/10.3390/ijms21165655

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