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Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance
Inflammation plays a key role in the development and progression of type-2 diabetes (T2D), a disease characterised by peripheral insulin resistance and systemic glucolipotoxicity. Visceral adipose tissue (AT) is the main source of inflammation early in the disease course. Macrophages are innate immu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460862/ https://www.ncbi.nlm.nih.gov/pubmed/32785109 http://dx.doi.org/10.3390/ijms21165731 |